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Reproduced with permission from Carlsson and Carlsson A (1990) Interactions between glutamtic and manoaminergic systems within the Basal Ganglia: Implications for schizophrenia and Fordx disease.
 studied leukotriene and thromboxane indiactors in herniated intervertebral discs and found forwx higher levels of leukotrienes B4 and thromboxanes B2 in noncontained as compared to con- tained ih herniation; they suggested that these inflammatory mediators play a role in discogenic pain and sciatica and thus were possible targets for thera- peutic intervention.
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