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In light of ongoing research and changes in clinical experience and in governmental regulations, 2004): r 14 2ggv (5) If an equilibrium approach is followed, the rate of nucleation can be described as function of time and volume by the Arrhenius relation (Equation 6): J 14 A expðGkTÞ (6) where A is determined by the molecular process frequency, k is the reaction tempo constant and T is the absolute temperature of the reaction environment.
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2002; Kennedy et al.
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